Programme  Titles  Presenters  Topics 
Lunch and Poster Session 2
Tuesday, January 30, 2018, 12:05-13:35
Hibiscus Room/Promenade
[P2.01]
Response of primary breast cancer stem cells to long-term exposure to reproductive hormones and their antagonists: A pre-clinical model for a BCSCs hormonopredictive assay
M. Nasr*1, M. Farghaly2, T. Elsaba3, M. Elmokhtar2, A. Abdelkareem2, H. Fakhry3, N. Mousa1
1Zewail City of Science and Technology, Egypt, 2Assiut University, Egypt, 3South Egypt Cancer Institute, Egypt
[P2.02]
Ameliorative and prophylactic potency of stem cell in medicine
T. Odinga*1,2, E.M. Eze1
1University of Port Harcourt, Nigeria, 2Rivers State University, Nigeria
[P2.03]
Evaluation of neurotoxic chemicals in human neural development using Embryonic Stem Cells (ESCs)
J-H. Lee, C. Ahn, S-Y. Park, J.Y. An, D.N. Tran, E-B. Jeung*
Chungbuk National University, Republic of Korea
[P2.04]
Graphenated highly anisotropic ceramic scaffolds for spontaneous neural differentiation of mesenchymal stem cells
I. Hussainova*1, M. Gasik2, J. Kazantseva3, R. Ivanov1
1Tallinn University of Technology, Estonia, 2AALTO University Foundation, Finland, 3Cellin Technologies LLC, Estonia
[P2.05]
Antibiotics target breast cancer stem cells by inhibiting mitochondrial respiration
E. Abad*, C. Mir, D. Potesil, Z. Zdrahal, M. Palomino-Schätzlein, R. Herance, A. Zorzano, D. Sebastian, M.E. Lleonart, A. Lyakhovich
Vall d'hebron Research Institute (VHIR), Spain
[P2.06]
New small molecular weight bioactive compounds for the in vitro control of melanoma CellProliferation and spreading
Q. ul-Ain*, K-S. Kochanek, M. Iqbal.Choudhary
University of Karachi, Pakistan
[P2.07]
Mesenchymal cells and FGF2 immunoreactivity during retinoic acid mediated pelvic zone formation in regenerating tail of tadpoles of Polypedates maculatus
J. Hota*, P.K. Mahapatra
Utkal University, India
[P2.08]
Cathepsin D: A protease attracts mesenchymal stem cells for homing to tumor sites
G. Vangala*, F. Imhoff, S. Baird
University of Otago, New Zealand
[P2.09]
Characterizing ptger4 as a target gene of autism protein e6ap
C. Amadei*1, J. El Hokayem1, M. Alessandri1,2, Z. Nawaz1
1University of Miami, USA, 2Nova Southeastern University, USA
[P2.10]
In vitro expanded MSCs are not recommended for cartilage tissue engineering
T. Jiang*1,2, L. Zheng1,2, J. Zhao1,2
1Guangxi Medical University, China, 2The First Affiliated Hospital of Guangxi Medical University, China
[P2.11]
Trans differentiation of bone marrow stromal cells to mature glial phenotype characterized with differential gene expression
N.B. Nazm Bojnordi*, G.H. Ghasemi
Mazandaran University of Medical Sciences, Iran
[P2.12]
Derivation of functional mature neurons from testicular Spermatogonia stem cells
M.N. Nazm Bojnordi*, G.H. Ghasemi, A. Shojaie
Mazandaran University of Medical Sciences, Iran
[P2.13]
Developing non-human primate cell lines using stem cell technology for biomedical research
O.A. Oyediran*, H.B. Quadri, A.W. Ramoni
University of Ibadan, Nigeria
[P2.14]
Clonal evolution reveals accumulating mutations in vivo from hematopoietic stem cell to B-lymphocytic lineage in chronic lymphocytic leukemia
C-L. Chiang*, E. Hu, G. Lozanski, T-J. Doong, A. Lozanski, J.A. Woyach, J.C. Byrd, L.J. Lee, N. Muthusamy
The Ohio State University, USA
[P2.15]
Geometrical control of stem cell fate by self-organization of cytoskeleton
M-H. Oh1, Y-Q. Chen1, M-C. Wu1, Y-K. Wang2, K-H. Lin1, A. Chiou1, J-C. Kuo*1
1National Yang-Ming University, Taiwan, 2National Cheng Kung University, Taiwan
[P2.16]
Epigenetic regulation by wnt signaling of cardiac neural crest progenitors
A. Vedenko*1,2, K.E. Hatzistergos2, J.I. Young1, J.T. Hecht4, S.H. Blanton1, W. Balkan2,3, J.M. Hare2,3
1John P. Hussman Institute for Human Genomics, USA, 2University of Miami, Miami, FL, USA, 3University of Texas Health, Houston, TX, USA
[P2.17]
Mitochondria-targeted antioxidative treatment attenuates accelerated senescence of neural progenitor cells induced by antiretroviral drugs 
M. Velichkovska*, D. Avila, M. Skowronska, L. Bertrand, B. Surnar, S. Dhar, M. Toborek
University of Miami, USA
[P2.18]
Integrative epigenetic and single-cell RNA-seq profiling of human hematopoietic stem cells reveals epigenetic reprogramming of enhancer and regulatory elements during normal aging
E. Adelman*1,2, A. Olsson3, T. Qin2, R. Lindsley4, R. Bejar5, N. Salomonis3, H. Grimes3, M. Figueroa1,2
1University of Miami Miller School of Medicine, USA, 2University of Michigan Medical School, USA, 3Cincinnati Children's Hospital, USA, 4Dana-Farber Cancer Institute, USA, 5University of California San Diego, USA
[P2.19]
GHRHR is a cell-surface marker of human pluripotent stem cell-derived cardiomyogenic precursors
K.H. Hatzistergos*, W.Y. Yu, A.V. Vedenko, K.V. Valasaki, W.B. Balkan, J.H. Hare
University of Miami, USA
[P2.20]
Interactions between adipocytes and breast cancer cells stimulate cytokine production and drive Src/SOX2/miR-302b mediated malignant progression
M. Picon-Ruiz*1,2, C. Pan1, K. Drews-Elger1, K. Jang1, A.H. Besser1, D. Zhao1, C. Morata-Tarifa1,2, M. Kim1, T.A. Ince1, D.J. Azzam1 et al
1University of Miami Miller School of Medicine, USA, 2University of Granada, Spain, 3Bruce W. Carter Veterans Affairs Medical Center, USA
[P2.21]
A novel fluorescent reporter mouse strain to non-invasively monitor transcription from gata6
R. Moore*, Y. Meng, W. Tao, E.R. Smith, X-X. Xu
University of Miami School of Medicine, USA
[P2.22]
Suppression of microRNA let-7a expression promotes neurogenesis in arginine decarboxylase-neural stem cells after ischemia
Y. Oh*1,2, J.Y. Kim1, J.Y. Kim1, S. Barua1, J.E. Lee1,2
1Yonsei University College of Medicine, Republic of Korea, 2Yonsei University, Republic of Korea
[P2.23]
Effect of local administration of mesenchymal stem cell therapy on auditory system in a rat model
R. Mittal*, E. Ocak, H. Jung, J. Mittal, A. Eshraghi
University of Miami Miller School of Medicine, USA
[P2.24]
Targeting HIV-infected brain to improve stroke outcome
L. Bertrand*, F. Méroth, A. Leda, M. Toborek
University of Miami, USA
[P2.25]
KCTD2 promotes E3 ubiquitin ligase-mediated degradation of c-Myc protein and suppresses glioblastoma progression
K. Eun*, E-J. Kim, H. Kim
Korea University, Republic of Korea
[P2.26]
Mesenchymal stem cells treatment of a mouse model of Alzheimer's disease
M. Pinto*, C. Premer, J.M. Hare, B.S. Baumel
University of Miami, USA
[P2.27]
A double suicide gene approach to prevent tumorigenesis and select β-Cells from hESc-differentiated progeny
M.M.F. Qadir*1, S. Alvarez-Cubela1, K. Belle1, T. Sapir1, F. Messaggio1, D. Hardin1, D. Klein1, I. Perez-Alvarez2, F. Sadiq3, J. Dominguez-Bendala1 et al
1University of Miami, USA, 2University of California Irvine Medical Center, USA, 3Florida Hospital, USA
[P2.28]
Detection and prevalence of PDX1+/ALK3bright+ progenitor-like cells in nPOD pancreatic samples from T1D patients
S. Alvarez-Cubela*1, R. Muniz1, M.M.F. Qadir1,2, D. Klein1, G. Lanzoni1, C. Garcia-Santana5, A. Montalvo1, F. Placeres-Uray1, C. Ricordi1,3, R.L. Pastori1,4, J. Dominguez-Bendala1,3 et al
1University of Miami, USA, 2University of Miami Miller School of Medicine, USA, 3Ophysio, Inc., USA
[P2.29]
Neural stem cell manipulation to identify brain cancer cell of origin
C. Ballabio*, M. Anderle, G. Aiello, D. Caron, L. Tiberi
University of Trento, Italy
[P2.30]
Postmitotic Neuron reprogramming into cancer cell
G. Aiello*, C. Ballabio, M. Anderle, D. Caron, L. Tiberi
CIBIO, Italy
[P2.31]
Derivation of hiPSC from peripheral blood mononuclear cells in cGMP condition
I. Krontorad Koutna*, P. Simara, L. Tesarova, A. Hampl
St. Anne's University Hospital - International Clinical Research center, Czech Republic
[P2.32]
Role of nitric oxide and s-nitrosylation in cardiomyogenesis by iPSCs 
A.G. Salerno*, K.E. Hatzistergos, R.A. Dulce, A.C.B.A. Wanschel, W. Balkan, J.M. Hare
University of Miami Miller School of Medicine, USA
[P2.33]
Enhanced therapeutic effects of mesenchymal stem cell spheroids using perfusion in a microfluidic platform
A.C. Bowles*1,2, D. Correa1,3, A. Agarwal1,2
1University of Miami, USA, 2DJTMF Biomedical Nanotechnology Institute, USA, 3Diabetes Research Institute, USA
[P2.34]
Silk fibroin/cartilage matrix biphasic scaffold, a suitable environment for hADSCs for osteochondral tissue engineering
N.K. Moncada-Saucedo*1, A. García-Ruiz1, V. Pérez-Silos1,2, A. Camacho-Morales1, V.J. Romero-Díaz1, Y. Castro-Govea1, E.E. Coronado-Cerda1, H. Lin2, R.S. Tuan2, L. Fuentes-Mera1 et al
1Universidad Autónoma de Nuevo León, Mexico, 2University of Pittsburgh, USA
[P2.35]
The effects of electronic cigarette vapor exposure on the osteogenic differentiation potential of human periodontal ligament derived stem cells
C. Carballosa*1,2, M. Salathe3, H. Cheung1,2
1University of Miami, USA, 2Miami Veterans Affairs Medical Center, USA, 3University of Miami Miller School of Medicine, USA
[P2.36]
Human umbilical cord blood-stem cells promote macrophage polarization through decorin in hyperoxic lung injury
J.H. Kwon*, H.J. Jin
Medipost Co., Ltd, Republic of Korea
[P2.37]
Secretome of human adipose-derived stem/ stromal cells reverts neuropathic pain, neuroinflammation and peripheral cytokines imbalance in a preclinical model of diabetes
A.T. Brini*1,2, G. Amodeo1, S. Niada1,2, L.M. Ferreira1,2, A. Milani1,2, G. Moschetti1, S. Franchi1, A.E. Panerai1, P. Sacerdote1
1Università degli Studi di Milano, Italy, 2IRCCS Galeazzi Orthopaedic Institute, Italy
[P2.38]
Effects of the G-quadruplex interacting agent RHPS4 on glioblastoma differentiated and cancer stem cells: an in vitro and in vivo study
M. Tanori*1, F. Berardinelli2, M. Mancuso1, A. Sgura2, A. Antoccia2
1ENEA, Italy, 2University Roma tre, Italy
[P2.39]
Phoshphorylated p27 promotes tumor-initiating ability and tumor metastasis by repressing PTPN12 gene
H. Yoon*, K. Jang, M. Kim, M. Shin, J.M. Slingerland
University of Miami, USA
[P2.40]
Maintenance and restoration of bronchial ciliated cell differentiation from basal stem cells in airway disease
N. Fregien*1, M. Valencia Gattas1, B. Gerovac2, G.E. Conner1
1University of Miami Miller School of Medicine, USA, 2Washington University School of Medicine, USA
[P2.41]
Targeting breast cancer stem cells
F.B. Bai1, S.L. Liu1, J.H. Herschkowitz2, C.P. Perou2, X.P. Pei*1
1University of Miami, USA, 2University of North Carolina, USA
[P2.42]
Phenotype of super-responders to stem cell therapy for non-ischemic dilated cardiomyopathy
A.C. Rieger*, V. Florea, B.A. Tompkins, M. Natsumeda, A.M. Landin, C. Premer, I. Schulman, J.M. Hare
University of Miami, USA
[P2.43]
Cell culture oxygen levels modify cord blood hematopoietic stem cell function
A.D. Henn*1, S.P. Hilchey2, J. Garigen2, S. Darou1, R. Yerden1, M.S. Zand2
1BioSpherix, USA, 2University of Rochester, USA
[P2.44]
Identification of non-catalytic targets of EZH2 in triple-negative breast cancer
M. Shin*, H. Yoon, D. Kwon, Y. Ban, Z. Gao, S.X. Chen, J.M. Slingerland
University of Miami, USA
[P2.45]
Optimizing stem cell transplant protocols to increase rate of stroke recovery
S. Sharififar1, K. Vyas1, D. Bennion1, D.D. Fuller1, C. Sumners1, H.H. Ross*2
1University of Florida, USA, 2Brenau University, USA
[P2.46]
Hypoxic preconditioning effects of hMSCs on oxidatively stressed cardiomyocytes
D. Hardin*1,2, J. Kuznetsoff1,2, W. Balkan1,2, J.M. Hare1,2
1Interdisciplinary Stem Cell Institute, USA, 2University of Miami Miller School of Medicine, USA
[P2.47]
Evaluating renal injury in a murine model after irradiation
A. Ahmad*1, A. Mitrofanova1, S. Ansari1, J.S.Y. Yang1, S. Merscher1, A. Fornoni1, Y. Zeidan2, B. Marples1
1University of Mimai, USA, 2American University of Beirut, Lebanon
[P2.48]
Transendocardial stem cell injection sites with higher voltage predicts cardiac function improvements in patients with non ischemic dilated cardiomyopathy
V. Florea*1, M. Natsumeda1, A.C. Rieger1, B.A. Tompkins1, M.N. Banerjee1, D.L. DiFede2, A. Khan1, J.M. Hare1, R.D. Mitrani1
1University of Miami Miller School of Medicine, USA, 2Longeveron LLC, USA
[P2.49]
A novel multifunctional assay for quantification and characterization of viable circulating tumor cells
Y. Yang*, R. Datar, P. Miller, U. Sharma, T. Giret, D. El-Ashry, R. Cote, S. Daunert
University of Miami, USA
[P2.50]
Sphere formation properties of peripheral nerve resident schwann cells and fibroblasts
P.V. Monje*, R. Graham, B. Kuo
University of Miami, USA
[P2.51]
iPSC-derived retinal organoids and CRISPR in a platform for retinoblastoma tumor progression modelling
Z. Acosta Torres*, J.W. Harbour, D. Pelaez
University of Miami, USA
[P2.52]
Defining in vitro skeletal myogenesis from human pluripotent stem cells using single cell RNA-sequencing
H. Xi*1, J. Langerman1, C.S. Young1, S. Sabri1, A.B. Mota1,2, M.J. Spencer1, K. Plath1, A.D. Pyle1
1University of California Los Angeles, USA, 2California State University Northridge, USA
[P2.53]
Identifying optimal donor characteristics for Mesenchymal Stem Cell proliferation for clinical applications
Z. Abdullah*, K. Valasaki, O. Malik, R. Silvera, A. Khan
University of Miami, USA
[P2.54]
O GlcNAc modification of SOX2 modulates its effect on invasion and self-renewal in Pancreatic Cancer
N.S. Sharma*1, V.K. Gupta1, P. Dauer2, K. Kesh1, V. Dudeja1, A. Saluja1, S. Banerjee1
1University of Miami, USA, 2University of Minnesota, USA
[P2.55]
Transforming growth factor-beta and lithium chloride preconditioning enhances the hair growth-promoting effects of human umbilical cord blood-derived mesenchymal stem cells
H.A. Oh1, J.H. Kwak*1, H.B. Jeon1, S.J. Choi1, W.I. Oh1, Y.S. Yang1, B.J. Lee2, J. Lee1, E.S. Jeon1
1MEDIPOST Co., Republic of Korea, 2Chung-Ang University College of Medicine, Republic of Korea
[P2.56]
Dormancy and activation mechanism of tracheal stem cells
X-S. Jia*1, F. Li2, X. Li1,3, W-Y. Li1, W-Z. Zhang1, Z-H. Ren1 et al
1China Medical University, China, 2IVF Michigan, USA, 3Shenyang Pharmaceutical University, China
[P2.57]
Radiation response of adipose-derived stem cells isolated from the female breast with special emphasis on interactions with breast cancer cells
A. Baaße*, F. Machoy, D. Juerß, E. Reape, K. Manda, G. Hildebrandt
University of Rostock, Germany
[P2.58]
Systemic delivery of stem cells to atherosclerotic lesions using novel nanocarrier in ApoE-/- mice
Z-J. Liu*, M.M. Regueiro, L. Zhang, Y. Li, S. Joel, G.S. O'Connor, S. Deo, S. Daunert, O.C. Velazquez
University of Miami, USA
[P2.59]
Investigating Axonal Biology Using iPSC-derived Human Motor Neuron Neurospheres
R. Maciel*, A. Cutupri, A. Rebelo, A. Abrams, S. Zuchner, M.A. Saporta
University of Miami Miller School of Medicine, USA
[P2.60]
Culture expansion of adult olfactory basal stem cells
R. Choi*, G.M. Goss, S. Kurtenbach, S. Goncalves, B.J. Goldstein
University of Miami, USA
[P2.61]
Identification of LBH, a WNT target transcriptional regulator in the etiology of aggressive basal-like breast cancer
K.J. Briegel*, P.P. Chen, K. Ashad-Bishop, L.E. Lindsey, M.E. Rieger, K. Garikapati, M. Jorda
University of Miami Miller School of Medicine, USA
[P2.62]
How do ES cells jump over their own shadow? - A knockout repository for the genetic dissection of the exit from pluripotency
A. Lackner*, R. Sehlke, M. Garmhausen, J. Ramesmayer, P. van der Lelij, A. Smith, A. Beyer, M. Leeb
University of Vienna, Austria
[P2.63]
Ex vivo expansion and transplantation of human hematopoietic stem cells
M.S. Baig
Indian Institute of Technology Indore, India
[P2.64]
Insights into structure and function of SHIP2-SH2
U. Saqib*1, I. Siddiqi2
1IIT, India, 2CDRI, India
[P2.65]
In vitro recapitulation of the dysfunctional neuromuscular junction in Charcot-Marie-Tooth disease
R. Besser*, I. Claure, D. Carbonero, R. Maciel, M. Saporta, A. Agarwal
University of Miami, USA