Programme  Titles  Presenters 
Tuesday, September 30, 2014
17:00-19:00  Registration
Jackson Park Foyer
 
Wednesday, October 1, 2014
07:30-09:00  Registration
Jackson Park Foyer
  Session 1- OMICS (metabolomics, lipidomics, proteomics)
Grant Park
09:00-09:10  Opening remarks
Grant Park
09:10-09:40  Christopher B. Newgard, Duke University School of Medicine, USA | Metabolomics defines cardiometabolic disease mechanisms
Grant Park
09:40-10:10  Jens Nielsen,Chalmers University of Technology, Sweden | Studies of metabolic diseases and cancer through genome scale modeling of human metabolism
Grant Park
10:10-10:25  Short talk 1 - Large-scale quantitative proteolipidomics delineates system-level food- and circadian rhythm-dependent regulation of lipid metabolism
Grant Park
10:25-10:55  Coffee break
Jackson Park
10:55-11:25  Benjamin F. Cravatt III, The Scripps Research Institute, USA | Activity-based proteomics - Applications for enzyme and inhibitor discovery
Grant Park
11:25-11:55  Eyal Gottlieb, University of Glasgow, UK | Targeting metabolic adaptations of cancer to stressful environmental conditions
Grant Park
11:55-12:10  Short talk 2 - Dynamics of histone methylation mediated by methionine availability and one carbon cycle flux
Grant Park
12:10-13:15  Lunch
Jackson Park
  Session 2 - Molecular circuits in metabolic diseases
Grant Park
13:15-14:00  Matthias Mann, Max Planck Institute, Germany | High-resolution (phospho)-proteomics in diabetes research
Grant Park
14:00-14:30  Joe Bass, Northwestern University, USA | Control of mitochondrial function by the Clock-NAD+-Sirtuin pathway
Grant Park
14:30-15:00  Jake Lusis, UCLA School of Medicine, USA | Systems genetics analysis of metabolic trait pathways using a panel of inbred mouse strains
Grant Park
15:00-15:15  Short talk 3 - Diet-microbiota interactions and their implication for host metabolism
Grant Park
15:15-15:45  Coffee break
Jackson Park
15:45-16:15  Ruth Loos, Mount Sinai Hospital, USA | The Genetics of common obesity - Gaining new insights through integrating data
Grant Park
16:15-16:45  Mark McCarthy, Oxford University, UK | Integrative genomics: From genotype to function in type 2 diabetes
Grant Park
16:45-17:00  Short talk 4 - Systems genetics analyses of human adipose tissue gene expression identify cis- and trans-regulatory networks for cardiometabolic traits
Grant Park
17:00-17:20  Poster teaser session
Grant Park
17:20-19:20  Poster session I and drinks reception
Jackson Park
 
Thursday, October 2, 2014
  Session 3 - Non-coding RNAs in metabolic diseases
Grant Park
09:00-09:30  Dimitrios Iliopoulos, University of California, USA | Regulation of metabolic circuits by non-coding RNAs
Grant Park
09:30-10:00  John Rinn, Harvard University/The Broad Institute, USA | Functional roles of long noncoding D/RNA in Metabolism
Grant Park
10:00-10:15  Short talk 5 - Genome-wide identification of microRNAs regulating cholesterol/lipid homeostasis
Grant Park
10:15-10:45  Coffee break
Jackson Park
10:45-11:15  Kathryn Moore, NYU Langone Medical Center, USA | Mechanisms of macrophage retention and chronic inflammation in metabolic diseases
Grant Park
11:15-11:45  Markus Stoffel, ETH Zürich, Switzerland | MicroRNA function in metabolism
Grant Park
11:45-12:00  Short talk 6 - Hepatic microRNA link glucocorticoid signaling to lipid metabolism
Grant Park
12:00-14:00  Poster session II and Lunch
Jackson Park
  Session 4 - Epigenomics and transcriptional metabolic networks
Grant Park
14:00-14:30  Susanne Mandrup, University of Southern Denmark, Denmark | Transcriptional networks regulating browning of human adipocytes
Grant Park
14:30-14:45  Short talk 7 - Histone carbonylation: A novel intersection between lipid metabolism and the epigenomic signature
Grant Park
14:45-15:15  Mitch Lazar, University of Pennsylvania, USA | Integrating metabolism around the clock
Grant Park
15:15-15:45  Coffee break
Jackson Park
15:45-16:15  Paolo Sassone-Corsi, University of California, USA | Epigenetics and metabolism: The circadian clock link
Grant Park
16:15-16:30  Short talk 8 - Early nutrition reprograms the hepatic Circadian Clock across multiple generations: Potential role of epigenetics
Grant Park
16:30-16:45  Short talk 9 - Mitochondrial sirtuin network reveals a novel role of SIRT3 in maintaining mitochondrial energy homeostasis
Grant Park
16:45-17:45  Meet the Editors
19:00-22:00  Meet the Speakers dinner
Berghoff Restaurant
 
Friday, October 3, 2014
  Session 5 - Therapeutically targeting metabolic circuits
Grant Park
09:00-09:30  David James, University of Sydney, Australia | The human exercise signaling landscape
Grant Park
09:30-10:00  Short talk 12 - Integrative physiological analysis of adipose tissue metabolism
Grant Park
10:00-10:15  Short talk 10 - Integrated hormonal actions broadens the therapeutic potential of endocine biologics for metabolic diseases
Grant Park
10:15-10:45  Coffee break
Jackson Park
10:45-11:15  Dan Rader, University of Pennsylvania, USA | New biology and therapeutic targets in lipid metabolism inspired by human genetics
Grant Park
11:15-11:30  Short talk 11 - Flavin monooxygenase 3 as a novel mediator of diabetes associated atherosclerosis
Grant Park
11:30-11:45  Short talk 13 - Serine deprivation enhances anti-neoplastic activity of biguanides
Grant Park
11:45-12:00  Closing remarks
Grant Park
 
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