Programme  Titles  Presenters 
Sunday 15th October 2017
12:30-14:40  Registration
Sunset Foyer
  Session 1: Metabolic Precision Therapies
Sunset Ballroom
14:40-14:50  Opening remarks: Matthias Tschӧp, Helmholtz Zentrum München; Nikla Emambokus, Editor-in-Chief, Cell Metabolism; Robert Kruger, Deputy Editor, Cell
Sunset Ballroom
14:50-15:30  [INV01] Chemical evolution of metabolic hormones , R. Di Marchi, Yale University, USA
Sunset Ballroom
15:30-16:10  [INV02] Locally complete, molecularly defined neuroscience of need states such as hunger , S. Sternson, Howard Hughes Medical Institute, USA
Sunset Ballroom
16:10-16:25  [ST01] Metabolic action of bispecific anti-FGFR1/âKlotho antibody in obese mice and humans
Sunset Ballroom
16:25-17:00  Refreshment break
Sunset Pavilion
  Session 1: Metabolic Precision Therapies (Contd.)
17:00-17:40  [INV03] New pathways of energy expenditure: The dominant role of adipose creatine metabolism, B. Spiegelman, Harvard University, USA
Sunset Ballroom
17:40-18:20  [INV04] Causes and consequences of obesity; lessons from human genetics, S.O. Rahilly, University of Cambridge, UK
Sunset Ballroom
18:20-18:35  [ST02] Monomethyl branched chain fatty acids link mitochondrial amino acid metabolism and adipose tissue lipogenesis to fatty acid diversity
Sunset Ballroom
18:35-18:50  [ST03] Therapeutic targeting of a thrifty microRNA in metabolic diseases
Sunset Ballroom
18:50-21:00  Welcome drinks reception & Poster session 1
Sunset Pavilion
 
Monday 16th October 2017
08:00-08:30  Morning coffee
Sunset Pavilion
  Session 2: Towards a future without diabetes
Sunset Ballroom
08:30-09:10  [INV05] TBC, B. Kahn, Harvard Medical School, USA
Sunset Ballroom
09:10-09:50  [INV06] FrancType 2 Diabetes: An operable (intestinal?) disease, F. Rubino, Kings College London, UK
Sunset Ballroom
09:50-10:05  [ST04] Dietary fructose is cleared by the small intestine
Sunset Ballroom
10:05-10:40  Refreshment break
Sunset Pavillion
  Session 2: Towards a future without diabetes continues...
Sunset Ballroom
10:40-11:20  [INV07] FXR and FGF-1: Resetting diabetes , R.M. Evans, Salk Institute, USA
Sunset Ballroom
11:20-12:00  [INV08] Toward metabolic precision medicines for obesity and type 2 diabetes, M. Tschop, Helmholtz Zentrum München, Germany
Sunset Ballroom
12:00-12:15  [ST05] FGF1 regulates adipose lipolysis to maintain glucose homeostasis
Sunset Ballroom
12:15-12:30  [ST06] Oxysterol signatures associated with impaired cholesterol metabolism distinguish age-related macular degeneration from physiologic aging
Sunset Ballroom
12:30-14:40  Lunch & Poster session 2
Sunset Pavilion
  Session 3: Obesity – Is it all in the mind?
Sunset Ballroom
14:40-15:20  [INV09] Defining the neurocircuitry underpinning energy homeostasis, L. Heisler, University of Aberdeen, UK
Sunset Ballroom
15:20-16:00  [INV10] Mitochondrial dynamics in metabolism regulation, S. Diano, Yale University, USA
Sunset Ballroom
16:00-16:30  Refreshment break
Sunset Pavilion
  Session 3: Obesity – Is it all in the mind? continues...
Sunset Ballroom
16:30-17:10  [INV11] Lateral hypothalamic circuits for feeding and reward, G. Stuber, The University of North Carolina, USA
Sunset Ballroom
17:10-17:25  [ST07] The MC4R agonist Setmelanotide (RM-493) potently reduces food intake and body weight in clinical monogenic obesity disorders associated with leptin-melanocortin pathway deficits
Sunset Ballroom
19:00-22:30  Meet the Speaker Dinner | Tom Hams Lighthouse (buses to depart at 18:30)
 
Tuesday 17th October 2017
08:00-08:30  Morning coffee
Sunset Pavilion
  Session 4: Translating therapeutics for metabolic diseases
Sunset Ballroom
09:00-09:40  [INV12] Cardiovascular biology of gut-based therapies for metabolic disease, D. Drucker, Lunenfeld-Tanenbaum Research Institute, Canada
Sunset Ballroom
09:40-10:20  [INV13] Metabolomics unveils cardiometabolic disease mechanisms and therapeutic strategies, C.B. Newgard, Duke University Medical Center, USA
Sunset Ballroom
10:20-10:35  [ST08] Mechanistic studies of the impact of microbially produced histidine-derived metabolites on insulin signaling
Sunset Ballroom
10:35-10:50  [ST09] Role of VEGF-B signalling in diabetic complications
Sunset Ballroom
10:50-11:20  Refreshment break
Sunset Pavilion
  Session 4: Translating therapeutics for metabolic diseases continues...
Sunset Ballroom
11:20-12:00  [INV14] The genetics of obesity - going beyond common variation and common phenotypes, R. Loos, Mount Sinai Hospital, USA
Sunset Ballroom
12:00-12:15  [ST10] Dietary fiber protects against diet induced obesity by altering gut microbiota and functions of GPR41 expressing cells
Sunset Ballroom
12:15-12:30  [ST11] Rapid regulation of hepatic lipid metabolism by modulation of bile acid fluxes in humans
Sunset Ballroom
12:30-13:30  Lunch
Sunset Pavilion
  Session 5: Integrated precision care
Sunset Ballroom
13:30-14:10  [INV15] TGR5 signaling and control of metabolism, K. Schoonjans, Ecole Polytechnique Fédérale de Lausanne, Switzerland
Sunset Ballroom
14:10-14:40  [INV16] Physiological functions of mitochondrial dynamics, D. Chan, California Institute of Technology, USA
Sunset Ballroom
14:40-14:55  [ST12] CerS6-derived sphingolipids promote mitochondrial fragmentation and insulin resistance in obesity through mitochondrial fission factor
Sunset Ballroom
14:55-15:30  Refreshment break
Sunset Pavilion
  Session 5: Integrated precision care continues...
Sunset Ballroom
15:30-16:50  [INV17] Our dynamic microbiomes and gut health, R. Knight, University of California, USA
Sunset Ballroom
16:10-16:50  [INV18] Role of ER stress in the pathogenesis of non-alcoholic steatohepatitis (NASH), M. Karin, University of California, USA
Sunset Ballroom
16:50-17:00  Closing remarks: Matthias Tschӧp, Helmholtz Zentrum München; Nikla Emambokus, Editor-in-Chief, Cell Metabolism; Robert Kruger, Deputy Editor, Cell
Sunset Ballroom
 
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