Programme  Titles  Presenters  Topics 
Sunday 19 March 2017
18:30-19:00  Registration
Main Foyer
19:00-19:10  Welcome and Opening Remarks, Philip T. LoVerde
Hyannisport East/West
19:10-20:10  [K01] Single-cell analysis of stem cells driving the schistosome life cycle, Phillip A Newmark, Howard Hughes Medical Institute, USA
Hyannisport East/West
20:10-22:00  Welcome Reception
Lobby Bar
 
Monday 20 March 2017
07:30-08:00  Registration
Grand Ballroom Lobby
08:00-08:15  Welcome and Opening Remarks- Sara Lustigman
Grand Ballroom II
08:15-10:35  Session: Helminth Genome Projects
Grand Ballroom II
08:15-08:45  [K02] The 50 Helminths genomes project: Searching for targets amongst one million new genes, Matthew Berriman, Wellcome Trust Sanger Institute, UK
Grand Ballroom II
08:45-09:10  [INV01] Knowledge based target and drug discovery, Makedonka Mitreva, Washington University School of Medicine, USA
Grand Ballroom II
09:10-09:35  [INV02] Comprehensive Echinococcus multilocularis life cycle- and stem cell-transcriptomic analyses, Klaus Brehm, University of Wurzburg, Germany
Grand Ballroom II
09:35-10:35  Wormbase Workshop- WormBase ParaSite: A comprehensive resource for helminths genomics
Grand Ballroom II
10:35-11:05  Refreshment break
Osterville Room
11:05-12:30  Session: 'Omics' of Helminths (Transcriptome, proteome, secretome, metabolome)
Grand Ballroom II
11:05-11:35  [K03] Understanding the immune response to infectious disease on a proteome-wide scale, Phil Felgner, University of California Irvine, USA
Grand Ballroom II
11:35-12:00  [INV03] Establishing an Controlled Human Hookworm Infection (CCHI) model, Jeff Bethony, George Washington University, USA
Grand Ballroom II
12:00-12:15  [ST01] Functional genomic studies to identify novel therapeutic targets against Schistosoma mansoni, Jim Collins III, UT Southwestern Medical Center, USA
Grand Ballroom II
12:15-12:30  [ST02] Parent-of-origin gene expression in male and female schistosome parasites: toward a better understanding of an evolutionary scandal?, Eve Toulza, Université de Perpignan Via Domitia, France
Grand Ballroom II
12:30-14:00  Lunch & Poster Session
Osterville Room
14:00-17:30  Session: Transcriptome and Proteome of Helminths
Grand Ballroom II
14:00-14:25  [INV04] Monitoring the effect of inhibitors of histone modifying enzymes on Schistosoma mansoni by large-scale transcriptome analyses, Sergio Verjovski-Almeida, University of Sao Paulo, Brazil
Grand Ballroom II
14:25-14:50  [INV05] Glycomics-based identification of schistosome glycan motifs implicated in parasite-host biology, Ron Hokke, University of Leiden, The Netherlands
Grand Ballroom II
14:50-15:15  [INV06] Post-genomic insights into filarial infections: From biomarkers to novel approaches to therapy, Tom Nutman, National Institutes of Health, USA
Grand Ballroom II
15:15-15:45  Refreshment Break
Osterville Room
15:45-16:10  [INV07] Development of selective inhibitors of Schistosoma mansoni histone deacetylase 8 as potential therapeutic agents, Raymond Pierce, Institut Pasteur, France
Grand Ballroom II
16:10-16:35  [INV08] Regulatory RNAs and their role in anthelmintic resistance in Haemonchus contortus, Eileen Devaney, University of Glasgow, Ireland
Grand Ballroom II
16:35-17:00  [INV09] Functional interplay between Brugia malayi and its Wolbachia symbiont, Sara Lustigman, New York Blood Center, USA
Grand Ballroom II
17:00-17:15  [ST03] Defining Brugia malayi and Wolbachia symbiosis by stage-specific Dual RNA-seq, Alexandra Grote, New York University, USA
Grand Ballroom II
17:15-17:30  [ST04] Investigating liver fluke glycosylating mechanisms for parasite control, Paul McVeigh, Queen’s University Belfast, UK
Grand Ballroom II
17:30-19:00  Social Hour and Poster Session continued
Osterville Room
 
Tuesday 21 March 2017
08:00-10:15  Session: Tools to Manipulate Helminth Gene Expression
Grand Ballroom II
08:00-08:25  [INV10] Manipulating the genome of Strongyloides spp.: Basic methods in transgenesis, first attempts at gene disruption and editing by CRISPR/Cas9 and strategies to create homozygous mutations, James Barron Lok, University of Pennsylvania, USA
Grand Ballroom II
08:25-08:50  [INV11] How Schistosomes change the human serum proteome, Patrick Skelly, Tufts University, USA
Grand Ballroom II
08:50-09:15  [INV12] On the abundant and fuzzy presence of host proteins in Taenia solium cysts, Juan Pedro LaClette, Universidad Nacional Autónoma de Mexico, Mexico
Grand Ballroom II
09:15-09:30  [ST05] Non-coding RNA and the neuropeptidergic system: Drivers of behavioural plasticity in nematodes?, Johnathan J Dalzell, Queen’s University Belfast, UK
Grand Ballroom II
09:30-09:45  [ST06] Exploiting regenerative screens in free-living planarians to discover novel anthelmintic ligands and targets, Johnathan Marchant, University of Minnesota Medical School, USA
Grand Ballroom II
09:45-10:00  [ST07] Discovery of benzimidazole resistance mechanisms using C. elegans natural diversity, Erik C Andersen, Northwestern University, USA
Grand Ballroom II
10:00-10:15  [ST08] Metabolite profiling of infection-associated metabolic markers of onchocerciasis, S. Bennuru, National Institutes of Health, USA
Grand Ballroom II
10:15-10:45  Refreshment break
Osterville Room
10:45-11:55  Session: Signaling Pathways and Biomakers in Helminths
Grand Ballroom II
10:45-11:10  [INV13] Extracellular RNA and vesicles in gastrointestinal and filarial nematodes: Functional and diagnostic implications, Amy Buck, University of Edinburgh, UK
Grand Ballroom II
11:10-11:25  [ST09] Wnt signaling in tapeworm larval development, Uriel Koziol, Universidad de la República, Uruguay
Grand Ballroom II
11:25-11:40  [ST10] A granulin growth factor secreted by the carcinogenic liver fluke, Opisthorchis viverrini, and its role in wound healing and carcinogenesis, Michael J Smout, James Cook University, Australia
Grand Ballroom II
11:40-11:55  [ST11] New approaches to adapting C. elegans to the study of parasite drug resistance and biology, Mostafa Zamanian, University of Wisconsin – Madison, USA
Grand Ballroom II
11:55-14:00  Lunch & Poster Session
Osterville Room
14:00-17:45  Session: Signaling Pathways and Biomarkers in Helminths continued
Grand Ballroom II
14:00-14:25  [INV14] Exploring the role of the ecdysone receptor in Brugia malayi development, Tom Unnasch, University of South Florida, USA
Grand Ballroom II
14:25-14:50  [INV15] Gonad-specific and pairing-dependent gene expression detected by comparative RNA-seq in Schistosoma mansoni, Thomas Quack, Justus-Liebig-University Giessen, Germany
Grand Ballroom II
14:50-15:15  [INV16] Evolutionary and functional aspects of Venus Kinase Receptors, Colette Dissous, Institut Pasteur, France
Grand Ballroom II
15:15-15:30  [ST12] The Ca2+-channel protein SmORAI-1 is important for the reproduction of Schistosoma mansoni, Alexandra Angrisano, Justus-Liebig-University Gießen, Germany
Grand Ballroom II
15:30-16:00  Refreshment break
Osterville Room
16:00-16:15  [ST13] Metabolic responses to infection with Schistosoma mansoni and treatment with praziquantel in pre-school and school-aged children, Gordana Panic, Swiss Tropical and Public Health Institute, Switzerland
Grand Ballroom II
16:15-16:30  [ST14] Impact of enteric parasites on intestinal microbiota diversity and metagenomic changes in rural Argentinian and Ecuadorian children, Rojelio Mejia, Baylor College of Medicine, USA
Grand Ballroom II
16:30-16:45  [Special Presentation][WK02] NIH funding opportunities and preclinical resources for researchers, Deirdre Joy, Program Officer- National Institutes of Health, USA
Grand Ballroom II
16:45-17:45  Round Table Discussion of the Future of Helminthology, Phil LoVerde & Sara Lustigman
Grand Ballroom II
19:00-22:00  Conference Dinner (Optional Ticketed Event)
Bass River Room
 
Wednesday 22 March 2017
08:00-12:20  Session: Genetics and Biochemistry of Drug Targets, Drug Action and Resistance
Grand Ballroom II
08:00-08:30  [K04] Ivermectin and filariae: New perspectives on mechanism of action, Timothy Geary, McGill University, Canada
Grand Ballroom II
08:30-08:55  [INV17] Multifaceted screening funnel to identify macrofilaricides for onchocerciasis, Judy Sakanari, University of California at San Francisco, USA
Grand Ballroom II
08:55-09:20  [INV18] Diversity: Four muscle nAChRs in Brugia, Richard J. Martin, Iowa State University, USA
Grand Ballroom II
09:20-09:45  [INV19] Linkage mapping and Schistosome biology, Timothy J.C. Anderson, Texas Biomedical Research Institute, USA
Grand Ballroom II
09:45-10:10  [INV20] Epidemiology and evolution of schistosomes in a changing world, Joanne Webster, Imperial College London, UK
Grand Ballroom II
10:10-10:35  [INV21] How do the macrocyclic lactones act against filarial nematodes?, Adrian J. Wolstenholme, University of Georgia, USA
Grand Ballroom II
10:35-11:05  Refreshment Break
Osterville Room
11:05-11:20  [ST15] Disrupting calcium regulation in schistosomes to enhance praziquantel efficacy,Geoffrey N Gobert, Queen’s University Belfast, UK
Grand Ballroom II
11:20-11:45  [INV22] Platyhelminth-Specific Rhodopsin Orphan Family: What are They and Why Should We Care?, Timothy A. Day, Iowa State University, USA
Grand Ballroom II
11:45-12:00  [ST16] Potent inhibitors of parasite neuromuscular function identified through high throughput screening against a schistosome serotonin receptor, John D Chan, University of Minnesota Medical School, USA
Grand Ballroom II
12:00-12:25  [INV23] Schistosomicidal oxamniquine derivative drug activity against human schistosomiasis, Philip T. LoVerde, University of Texas Health Center, USA
Grand Ballroom II
12:25-12:35  Closing Remarks
Grand Ballroom II
 
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